{"id":5239,"date":"2004-04-21T13:17:07","date_gmt":"2004-04-21T20:17:07","guid":{"rendered":"http:\/\/hill-kleerup.org\/blog\/wp\/2004\/04\/21\/ive-been-dreaming-about-this-since-dr-mccoy.html"},"modified":"2004-04-21T13:17:07","modified_gmt":"2004-04-21T20:17:07","slug":"ive_been_dreami","status":"publish","type":"post","link":"https:\/\/hill-kleerup.org\/blog\/2004\/04\/21\/ive_been_dreami.html","title":{"rendered":"I&#8217;ve been dreaming about this since Dr. McCoy &#8230;"},"content":{"rendered":"<p>Injections without needles?  <a title=\"Science &#038; Technology at Scientific American.com: New Drug Delivery Technique Avoids Needles\" href=\"http:\/\/www.sciam.com\/article.cfm?chanID=sa003&#038;articleID=00088955-60C6-1080-902183414B7F0000\">Far out<\/a>.<\/p>\n<p class=\"block\">James Weaver of the Massachusetts Institute of Technology and his colleagues developed the novel procedure, which is known as microscission. It uses minuscule inert crystals of aluminum oxide to remove the rough outer layer of skin and create tiny holes, known as microconduits and measuring less than a quarter of a millimeter in diameter, through which medication can move. A jet of flowing gas then takes the crystals and the loosened skin away. After creating four microconduits on the inner arm of volunteers, the team applied a pad soaked in the anesthetic lidocaine. Within two minutes, the drug had worked and the subjects reported no feeling in the region. <br \/>\nThe size and depth of the microconduits is determined by holes punched in a polymer mask laid on top of the skin. The team reports that &#8220;the onset of anesthesia takes longer in microconduits deep enough to yield blood than in shallower, nonblood producing microconduits.&#8221; But deep microconduits do have some advantages. Patients suffering from diabetes, for example, often have to jab a finger to test their blood sugar; microscission could represent a less painful alternative, the team suggests.<\/p>\n<p>Not quite a &#8220;hypospray,&#8221; but getting there &#8230;<\/p>\n<p><small>(via <a href=\"http:\/\/www.geekpress.com\/2004_04_20_daily.html#108243279070368799\">GeekPress<\/a>)<\/small><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Injections without needles? Far out. James Weaver of the Massachusetts Institute of Technology and his colleagues developed the novel procedure, which is known as microscission. It uses minuscule inert crystals&#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_analysis_target_kw":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":false,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[20],"tags":[],"class_list":["post-5239","post","type-post","status-publish","format-standard","hentry","category-hi-tech"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack-related-posts":[{"id":48742,"url":"https:\/\/hill-kleerup.org\/blog\/2014\/12\/08\/snowflakes-are-awesomely-cool.html","url_meta":{"origin":5239,"position":0},"title":"Snowflakes are awesomely cool","author":"***Dave","date":"Mon 8-Dec-14 9:39pm","format":false,"excerpt":"I say, non-ironically, that these invoke for me memories of the \"Mighty Microscope\" from the Monstanto \"Adventure into Inner Space\" ride at Disneyland (http:\/\/en.wikipedia.org\/wiki\/Adventure_Thru_Inner_Space). Only ... for real. Originally shared by +Charles Carrigan: Gorgeous examples of snowflakes, taken by low-temperature scanning electron microscope (LT-SEM). The crystal structure of ice is\u2026","rel":"","context":"In &quot;~PlusPosts&quot;","block_context":{"text":"~PlusPosts","link":"https:\/\/hill-kleerup.org\/blog\/category\/blogging\/plusposts"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":16281,"url":"https:\/\/hill-kleerup.org\/blog\/2009\/11\/25\/unblogged-bits-early-edition.html","url_meta":{"origin":5239,"position":1},"title":"Unblogged Bits (early edition)","author":"***Dave","date":"Wed 25-Nov-09 9:34am","format":false,"excerpt":"Still experimenting. We've replaced Dave's Google Reader Shares with Folger's Crystals. Let's see what happens ... [recreading]","rel":"","context":"In &quot;Potpourri&quot;","block_context":{"text":"Potpourri","link":"https:\/\/hill-kleerup.org\/blog\/category\/potpourri"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":14351,"url":"https:\/\/hill-kleerup.org\/blog\/2009\/03\/27\/testing-posting-by-email-again.html","url_meta":{"origin":5239,"position":2},"title":"Testing posting by email (again)","author":"***Dave","date":"Fri 27-Mar-09 7:12pm","format":false,"excerpt":"We've replaced the post-by-email system that WP usually uses with Folge= rs Crystals.=C2=A0 Let's see what happens.","rel":"","context":"With 1 comment","block_context":{"text":"With 1 comment","link":"https:\/\/hill-kleerup.org\/blog\/2009\/03\/27\/testing-posting-by-email-again.html#comments"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":10006,"url":"https:\/\/hill-kleerup.org\/blog\/2006\/09\/27\/in_a_canyon_in_a_cavern.html","url_meta":{"origin":5239,"position":3},"title":"In a canyon, in a cavern &#8230;","author":"***Dave","date":"Wed 27-Sep-06 8:43pm","format":false,"excerpt":"Once upon a time, back when our KOA Camping Trip was still being held in Kings Canyon National Park, we used to take a trip every couple of years to...","rel":"","context":"In &quot;Travel&quot;","block_context":{"text":"Travel","link":"https:\/\/hill-kleerup.org\/blog\/category\/travel"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":6699,"url":"https:\/\/hill-kleerup.org\/blog\/2004\/07\/31\/life_during_the.html","url_meta":{"origin":5239,"position":4},"title":"Life during the plague","author":"***Dave","date":"Sat 31-Jul-04 8:03am","format":false,"excerpt":"\"Sequencing the whole genome has revealed that the bacterium can actively degrade human skin tissue because of the massive presence of these enzymes, and also that there are specific immunogenic...","rel":"","context":"In &quot;Science &amp; Nature&quot;","block_context":{"text":"Science &amp; Nature","link":"https:\/\/hill-kleerup.org\/blog\/category\/science"},"img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":10796,"url":"https:\/\/hill-kleerup.org\/blog\/2007\/06\/30\/potpourri_for_another_sat.html","url_meta":{"origin":5239,"position":5},"title":"Potpourri for another Saturday on Vacation","author":"***Dave","date":"Sat 30-Jun-07 7:37am","format":false,"excerpt":"Robo-Dave suggests: The Sins of PowerPoint. For the love of God, send this to all your business associates. How to maintain classroom discipline ... 1950s style. Folks who do pot...","rel":"","context":"In &quot;Job Jollies&quot;","block_context":{"text":"Job Jollies","link":"https:\/\/hill-kleerup.org\/blog\/category\/job-jollies"},"img":{"alt_text":"","src":"https:\/\/i0.wp.com\/www.hill-kleerup.org\/blog\/images\/giantrobot.jpg?resize=350%2C200&ssl=1","width":350,"height":200},"classes":[]}],"_links":{"self":[{"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/posts\/5239","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/comments?post=5239"}],"version-history":[{"count":0,"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/posts\/5239\/revisions"}],"wp:attachment":[{"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/media?parent=5239"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/categories?post=5239"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/hill-kleerup.org\/blog\/wp-json\/wp\/v2\/tags?post=5239"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}