It’s not just good, it’s good for you!
Huge amounts of a red wine extract seemed to help obese mice eat a high-fat diet and still live a long and healthy life, suggests a new study that some experts are calling “landmark” research.
The big question is, can it work the same magic in humans? Scientists say it’s far too early to start swilling barrels of red wine. But some are calling the latest research promising and even “spectacular.”
Never mind what the scientists say! I’m all in favor of amateur contributions to this research — sort of a SYRAH-at-Home kind of program!
The study by the Harvard Medical School and the National Institute of Aging shows that heavy doses of red wine extract lowers the rate of diabetes, liver problems and other fat-related ill effects in obese mice. Fat-related deaths dropped 31 percent for obese mice on the supplement, compared to untreated obese mice, and the treated mice also lived long after they should have, the study said.
Astoundingly, the organs of the fat mice that got the wine extract looked normal when they shouldn’t have, said study lead author Dr. David Sinclair of Harvard Medical School. And Sinclair said other preliminary work still being done in the lab shows the wine ingredient has promise in lengthening the life span of normal-sized mice, too.
I’ll drink to that!
Resveratrol, produced when plants are under stress, are found in the skin of grapes and in other plants, including peanuts and some berries.The resveratrol-treated 55 obese mice on a high-calorie diet (one scientist called it a “McDonald’s diet”) are not only about as healthy as normal mice, they are as agile and active on exercise equipment as their lean cousins, showing what can be considered a normal quality of life, higher than usual for obese mice, said study co-author Rafael de Cabo of the National Institute
on Aging.“These fat old mice can perform as well on this skill test as young lean mice,” Sinclair said. The only major body measurement that didn’t improve – aside from weight – was cholesterol and that didn’t seem to matter in the overall health of the mice, Sinclair said.
The study is so promising that the aging institute this week is strongly considering a repeat of the same experiment with rhesus monkeys, coming the closest to humans, after successful resveratrol experiments on yeast, worms, fruit flies and now mice, said institute director Dr. Richard Hodes.
[…] Sinclair said he takes resveratrol supplements, but doesn’t recommend it for others. Sinclair’s mice took such high doses of resveratrol that it would be the equivalent of an adult drinking 100 bottles of wine daily.
Hmmm. Maybe I’ll work on the efficacy of slightly lower doses …
(via Avo)